Indian Plant Antiviral Compound Database (IMPAC)
| Indian Plant Antiviral Compound | Description |
|---|---|
| InAVPCDB Accession Number | AVD041 |
| Compound Name | P-coumaric acid |
| Phytochemical category | Phenol |
| PubChem Id | 637542 |
| IUPAC Name | (E)-3-(4-hydroxyphenyl)prop-2-enoic acid |
| Molecular Formula | C9H8O3 |
| Canonical SMILES Notation | C1=CC(=CC=C1C=CC(=O)O)O |
| Binomial Name | Elephantopus scaber |
| Vernacular Names | Anashovadi/Samdudri/Enugabira/Elephant foot |
| Plant Part | Leaf |
| Family | Asteraceae |
| Description | Herpes simplex virus-1 and SARS-CoV-2. |
| Mechanism of action | It inhibits the viral proteases. |
| Molecular weight | 164.16 g/mol |
| XLOGP3 | 1.46 |
| Num. H-bond acceptors | 3 |
| Num. H-bond donors | 2 |
| Rotatable bonds | 2 |
| Topological polar surface area | 57.53 Ų |
| Bioavailability Score | 0.85 |
| Druglikeness | Yes |
| Lipinski | 0 violation |
| References | Hossain MK, Choi HY, Hwang JS, Dayem AA, Kim JH, Kim YB, Poo H, Cho SG. Antiviral activity of 3, 4?-dihydroxyflavone on influenza a virus. Journal of Microbiology. 2014 Jun 1;52(6):521-6. Schnitzler P, Neuner A, Nolkemper S, Zundel C, Nowack H, Sensch KH, Reichling J. Antiviral activity and mode of action of propolis extracts and selected compounds. Phytotherapy Research. 2010 Jan;24(S1):S20-8. |
