Indian Plant Antiviral Compound Database (IMPAC)
| Indian Plant Antiviral Compound | Description |
|---|---|
| InAVPCDB Accession Number | AVD036 |
| Compound Name | Mulberroside C |
| Phytochemical category | Flavanoid |
| PubChem Id | 190453 |
| IUPAC Name | (2S,3R,4S,5R)-2-[3-hydroxy-5-(6-hydroxy-7,7-dimethyl-5,6-dihydrofuro[3,2-g]chromen-2-yl)phenoxy]oxane-3,4,5-triol |
| Molecular Formula | C24H26O9 |
| Canonical SMILES Notation | CC1(C(CC2=C(O1)C=C3C(=C2)C=C(O3)C4=CC(=CC(=C4)OC5C(C(C(CO5)O)O)O)O)O)C |
| Binomial Name | Phyllanthus emblica |
| Vernacular Names | Nellikai/Anwala/Amla |
| Plant Part | Fruit |
| Family | Phyllanthaceae |
| Description | Enterovirus 71 (EV71) and Herpes viruses. |
| Mechanism of action | It inhibits the early stages of viral replication by targeting viral capsid. |
| Molecular weight | 486.68 g/mol |
| XLOGP3 | 1.54 |
| Num. H-bond acceptors | 9 |
| Num. H-bond donors | 5 |
| Rotatable bonds | 3 |
| Topological polar surface area | 141.98 Ų |
| Bioavailability Score | 0.55 |
| Druglikeness | Yes |
| Lipinski | 0 violation |
| References | Cao Y, Lei E, Li L, Ren J, He X, Yang J, Wang S. Antiviral activity of Mulberroside C against enterovirus A71 in vitro and in vivo. European Journal of Pharmacology. 2021 May 26:174204. Du J, He ZD, Jiang RW, Ye WC, Xu HX, But PP. Antiviral flavonoids from the root bark of Morus alba L. Phytochemistry. 2003 Apr 1;62(8):1235-8. |
