Indian Plant Antiviral Compound Database (IMPAC)
| Indian Plant Antiviral Compound | Description |
|---|---|
| InAVPCDB Accession Number | AVD047 |
| Compound Name | Trans-anethole |
| Phytochemical category | Monomethoxybenzene |
| PubChem Id | 637563 |
| IUPAC Name | 1-methoxy-4-[(E)-prop-1-enyl]benzene |
| Molecular Formula | C10H12O |
| Canonical SMILES Notation | CC=CC1=CC=C(C=C1)OC |
| Binomial Name | Foeniculum vulgare |
| Vernacular Names | Sombu/Perunjeeragam/Pedhajilakarra/sweet fennel |
| Plant Part | Seed |
| Family | Apiaceae |
| Description | Herpes simplex virus type 1 and SARS-CoV-2. |
| Mechanism of action | It inhibits specifically the viral DNA polymerase during the replicationcycle when new viral DNA is synthesized. |
| Molecular weight | 148.20 g/mol |
| XLOGP3 | 3.3 |
| Num. H-bond acceptors | 1 |
| Num. H-bond donors | 0 |
| Rotatable bonds | 2 |
| Topological polar surface area | 9.23 Ų |
| Bioavailability Score | 0.55 |
| Druglikeness | Yes |
| Lipinski | 0 violation |
| References | Astani A, Reichling J, Schnitzler P. Screening for antiviral activities of isolated compounds from essential oils. Evidence-based complementary and alternative medicine. 2011 Jan 1;2011. |
