Indian Plant Antiviral Compound Database (IMPAC)
| Indian Plant Antiviral Compound | Description |
|---|---|
| InAVPCDB Accession Number | AVD044 |
| Compound Name | Quercetin |
| Phytochemical category | polyphenolic flavanoid |
| PubChem Id | 5280343 |
| IUPAC Name | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one |
| Molecular Formula | C15H10O7 |
| Canonical SMILES Notation | C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O |
| Binomial Name | Allium ascalonicum |
| Vernacular Names | Chinna vengayam/Shallots |
| Plant Part | Bulb |
| Family | Liliaceae |
| Description | Dengue virus, Herpes viruses, and Influenza A virus |
| Mechanism of action | It inhibits different stages of intracellular replication of DENV-2 instead of early stages of its replication cycle such as virus attachment or entry.? |
| Molecular weight | 302.24 g/mol |
| XLOGP3 | 1.54 |
| Num. H-bond acceptors | 7 |
| Num. H-bond donors | 5 |
| Rotatable bonds | 1 |
| Topological polar surface area | 131.36 Ų |
| Bioavailability Score | 0.55 |
| Druglikeness | Yes |
| Lipinski | 0 violation |
| References | Zandi K, Teoh BT, Sam SS, Wong PF, Mustafa MR, AbuBakar S. Antiviral activity of four types of bioflavonoid against dengue virus type-2. Virology journal. 2011 Dec;8(1):1-1. Wu W, Li R, Li X, He J, Jiang S, Liu S, Yang J. Quercetin as an antiviral agent inhibits influenza A virus (IAV) entry. Viruses. 2016 Jan;8(1):6. |
