Indian Plant Antiviral Compound Database (IMPAC)
| Indian Plant Antiviral Compound | Description |
|---|---|
| InAVPCDB Accession Number | AVD020 |
| Compound Name | Eugenol |
| Phytochemical category | Phenyl Propanoid |
| PubChem Id | 3314 |
| IUPAC Name | 2-methoxy-4-prop-2-enylphenol |
| Molecular Formula | C10H12O2 |
| Canonical SMILES Notation | COC1=C(C=CC(=C1)CC=C)O |
| Binomial Name | Syzygium aromaticum |
| Vernacular Names | Kirambu/laung/clove |
| Plant Part | Flower bud |
| Family | ?Myrtaceae |
| Description | Feline calicivirus, Tomato yellow leaf curl virus, Influenza A virus, Herpes Simplex virus type 1 and 2, and Ebola virus. |
| Mechanism of action | It suppress the viral infection by inhibting viral replication process |
| Molecular weight | 164.20 g/mol |
| XLOGP3 | 2.27 |
| Num. H-bond acceptors | 2 |
| Num. H-bond donors | 1 |
| Rotatable bonds | 3 |
| Topological polar surface area | 29.46 Ų |
| Bioavailability Score | 0.55 |
| Druglikeness | Yes |
| Lipinski | 0 violation |
| References | Lane T, Anantpadma M, Freundlich JS, Davey RA, Madrid PB, Ekins S. The natural product eugenol is an inhibitor of the ebola virus in vitro. Pharmaceutical research. 2019 Jul;36(7):1-6. Gavanji S, Sayedipour SS, Larki B, Bakhtari A. Antiviral activity of some plant oils against herpes simplex virus type 1 in Vero cell culture. Journal of Acute Medicine. 2015 Sep 1;5(3):62-8. |
